Phenotypic and genotypic characteristics of japanese encephalitis live attenuated vaccine virus sa14 - 14 - 2 and its stability 2弱毒株的表型和基因型特性及其穩定性
But ib attenuated vaccine has many defects , such as the possibility of contamination of foreign and vertical transmissible pathogens , and the virulent recovery of vaccine virus . therefore , exploring the safe and efficient new vaccines has become the hotspot in the research of ib control 由于活疫苗存在外源性或垂直傳播性病原污染、毒力返祖等缺陷,開發安全、有效的新型疫苗是ib控制的研究重點。
Since last saturday inject the second medicinal preparation , the vaccine virus enters in body , changed except the personality has been dissimilar , rested compared to before goes to sleep with difficulty , last night even the whole body had a fever , she still continue to groan until 2 o ' clock before dawn so that mother was unable relieved to sleep asks for leave in the home rests 自從上星期六打完六合一第二劑之后,金柏?因為疫苗的病毒進入體內,除了性情變了不一樣,睡上比以前更難以入眠,昨晚甚至全身疑似發燒的狀況,直到凌晨二點仍然持續在呻吟,以致于媽媽無法安心睡覺而請假在家休息。
The phylogenetic tree was constructed based on sequence comparison and analysis . the result showed that c strain derived from rabbit spleen tissue , c strain adapted to sk6 cell , shimen virulent strain all belonged to group 1 . 1 , and the prevalent virulent strains belonged to subgroup 2 . 1 or subgroup 2 . 2 . this indicated there were at least two subgroups , which were prevailing in china , and the prevalent virulent strains were diverse far from c . strain vaccine virus 通過序列比較和系統發生關系分析發現: c -株兔組織毒、 c ?株細胞毒和中國50 60年代流行的石門強毒株同屬于組群1 ( group1 ) ;近期豬瘟流行毒株均屬于組群2 ( group2 )的兩個不同的亞組群( subgroup2 . 1和2 . 2 ) ,表明我國目前流行毒株至少有2個亞組群。
There were little difference in the amino acid composition of antigen domain of a , b and c between c strain from rabbit spleen tissue and virulent strains above . this indicated that the prevalence of csf and immunal failure may be not caused by the antigen variation of c stain vaccine virus . the e2 genes of 51 csfv prevalent virulent strains isolated from 12 provinces in china were amplified and sequencd 對c -株兔脾毒與c -株細胞毒、經典強毒e2上的a 、 b 、 c三個中和性抗原區的氨基酸組成進行了比較,其結果為: c -株兔脾毒與c -株疫苗細胞毒的差異很小甚至沒有差異。
Four mcabs were developed and can detect the meq gene expression in the cef infected with oncogenic mdvs and naturally occurred md tumor cells by fa and immunohistochemistry technique respectively , but ca n ' t detect that in the cef and normal chicken liver tissue respectively infected with non - virulent vaccine virus cvi988 / rispens . the results demonstrated that meq is highly expressed in t 獲得4株穩定產生抗meq蛋白mcab的雜交瘤細胞,其中3g12e6單抗通過fa和免疫酶組化技術能夠檢測到mdv致瘤株感染的cef及自然md腫瘤細胞中表達的me叮基因產物,而在非致瘤株cvi988 / rispens感染的cef和免疫的正常雞的組織中則未檢測到。